Derminator



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Messages - SarahVaughter

1846
The tissue half-life is always 4 days, regardless of how much vit. C you have loaded your skin with. This means that after about three days it starts to be a good idea to re-apply one application. Let`s say your skin has 256 mg/kg vit. C in it.  After 4 days, it only has 128 mg/kg, after 4 more days 64 mg/kg, after 4 more days 32 mg/kg etc. The same formula applies with any number of applications, serum strengths etc.

So, if you start with less vit. C because you had applied less often, initially you would have for ex. 64 mg/kg, 4 days later 32 mg/kg, 8 days after initial application 16 mg/kg etc.

1847
Ingredients should be just water and pure vit. C, as described on page 5 in our instructions here:

http://lufenuroncandidacure.owndoc.com/lufenuron.pdf

1848
As long as you avoid strong sun exposure longer than a couple of minutes, you`ll be OK.

1849
Dermarolling / Microneedling / Copper peptides
« on: May 17, 2010, 04:32:25 AM »
I'd use a mask once a week, but I advise trying it first after dermarolling with 0.25 mm needles first, because the concentration of peptides is high in our facial mask and redness is to be expected. I'll add this to the instructions.

1850
Dermarolling / Microneedling / Using makeup after dermarolling
« on: May 17, 2010, 04:29:38 AM »

Very much research has been done on the potential danger of chemicals used in makeup products, especially chemicals that work as hormones in the body and can contribute to breast cancer etc.

It is not within the scope of microneedling to understand the processes of skin absorbtion of intact skin, so I'm afraid I can't help you there.

But in general I can tell you that the absorbtion of chemicals into the skin depends on their water- and fat-solubility, the size of their molecule, whether they are ionized, how long they are applied etc.

So, no general rules can be given. All chemicals have wildly different skin penetration characteristics and I am sure that a lot of the marketing is just hype.

It could be theoretically possible that certain manufacturers of certain "skin penetrating" creams add solvents such as DMSO. That would increase penetration for certain chemicals.

1851
Dermarolling / Microneedling / Narrow 2 mm roller
« on: May 12, 2010, 04:13:57 PM »
Not soon, but we will order some and add them to the store. It will take at least one month though. So don't hold your breath - feel free to order elsewhere - it may take quite a bit longer than one month too.

1852
Please refer to page 5 of our dermarolling instructions:

http://dermaroller.owndoc.com/dermaroller-instructions.pdf

1853
Hi Katarina,

Here is a link to our web store:

http://webshop.owndoc.com/index.php?main_page=index&cPath=1

1854
Dermarolling / Microneedling / single needling bruises
« on: May 11, 2010, 01:53:01 PM »
Yes, the skin on the arms is thinner than that on the legs.

 

 It is impossible to sell a universal length needle that fits every skin condition and every part of the body, because firstly: Skin thickness varies significantly, depending on what part of the body it covers. The thinnest skin is on the eyelids (0.5 mm or less) the thickest is on the soles of the feet. The back and the buttocks have thick skin as well.

 Secondly, it also varies individually. We have customers that roll their face with a 2 mm roller and  they get no pinpoint bleeding and we have customers that roll their face with 0.5 mm and they get quite some pinpoint bleeding. And men usually have thicker skin than women.

 I am really sorry it caused you bruising on your arms but the good news  is that the release of blood may infact improve your stretchmarks. You caused a microwound to the skin, the body will fix it and fill the microwound with  new skin. That is the principle behind dermarolling and in fact, the literature suggests that blood plasma helps with this process. Do not get me wrong. You do not have to cause bleeding in order to improve the stretchmarks but apart from the cosmetic problem of being bruised, you do not have to worry too much about it either. Some surgeons even use dermarollers with 3 mm needles. We can even order those for our customers.

 You should not needle deeper than occasional pinpoint bleeding but the line between pinpoint bleeding and getting bruises is a fine line and it is difficult to guess.the best is to try a small patch first. Our needles have a "safety stop" at around 2 mm, but some needles are longer than others, so that you can choose which one suits a particular skin area best. You should not always put the needle in until it can't go any further - not on thin skin in any case.

 The skin consists of the epidermis, the dermis and the subdermis (fat layer).

 

 The epidermis has no blood supply at all.  If you get pinpoint bleeding it means you reached the dermis. The dermis has irregular tiny blood vessels and the deeper you go into the dermis, the more blood vessels there are. If you reach the deeper parts of the dermis where there are many bloodvessels, you could end up with bruises.

 

 Stretchmarks reside in  the dermis. As said, skin thickness is not the same all over the body, unfortunately.

 

You can adjust the needle length with a toothpick, so that you can let them penetrate only a mm, for example:  

 http://forums.owndoc.com/dermarolling-microneedling/Adjusting-the-length-of-the-single-needle

 

 The "toothpick solution" is not ideal but it's the best we found so far. So, next time when you needle your arms, use a toothpick to make it shorter.  

 

 We are trying to improve our products to our customers'  needs and I hope we can find a better solution. As I explained, it is impossible to sell a universal length that would be perfect for every condition and every customer. We still haven't found a needle manufacturer that can produce the perfect needle in a range of perfectly accurate lengths in the mm range. I hope next year we will have found such a supplier, but the current needles are in fact very good already, as long as you are aware that for some skin, they are a bit too long and should be either not pushed in to the hilt, or shortened with a taped toothpick to the shaft.

 Regarding bruises: You can use a cream containing heparin (available OTC in pharmacies), which will make the bruises disappear quicker. Do not apply Heparin cream immediately after needling (do not use it on "open" skin). Wait one day.  

 

Haley I am sorry you got bruises! Hopefully you'lll be rewarded with a solid improvement of your stretch marks.

1855
Dermarolling / Microneedling / Copper peptides-
« on: May 10, 2010, 05:27:34 PM »
We've asked for a price and a minimum order was 660 tubes for 9000 USD, ex. VAT, ex shipping. So I guess the answer is "no, for the time being".

We never understood why those "face masks" were so cheap compared to copper peptides, now we found out - they are not what we expected to be - cream - but physical masks with holes in them..

So if it's not mainly the face you want to improve, it's best to buy a tube of copper peptides somewhere else, sorry..

If it's the face that needs the most attention, then our masks are the best available today, due to the plethora of other ingredients such as vitamins B.

1856
Dermarolling / Microneedling / Air travel
« on: May 10, 2010, 05:23:17 PM »
Fortunately, there are no restrictions regarding flying and micro-needling. All that happens in an airplane is that the air pressure is a bit lower, such as at a moderate altitude on Earth. And you may have some impaired circulation. Nothing that affects the skin, neither does microneedling bring for ex. gasses into solution in the blood, as with diving (divers can't fly after a deep dive).

1857
Hi Chrystal,

   A relief to read your full question because when I read the title, I thought it was about dermarolling as a weight loss method which of course doesn't work.. :)

When I read those claims on how dermarolling will reverse gray hair, make stretchmarks and cellulite fully and quickly disappear and so on, I get frustrated because when people have unrealistic expectations, they will be disappointed.

I always try to inform our customers to the best of my ability, and of course I don't know everything. Dermarolling is a relatively new method and many aspects of it are not yet fully clear to anyone.

Regarding your question: It is OK to roll during weight loss. No
problem.

  What is very important is that you do not fluctuate too much in weight.
Significant weight fluctuations usually causes stretchmarks and the skin´s elasticity suffers. As to stretch marks: It is better to be steadily overweight than going frequently very much up and down in weight.

  So if you might not be able to keep the lost
               weight off, then better think twice about losing a lot of weight because if you gain it back you might end up with more stretchmarks.

Good luck!

1858
Dermarolling / Microneedling / Copper peptides
« on: May 05, 2010, 06:40:17 AM »
I re-post the essence here after erroneously having deleted the entire thread:

We have received the copper peptide facial masks. They are non-comedogenic.

We sell the GHK-Cu facial masks for just 3 dollars, and they are excellent after dermarolling the face with needles of any length.  The facial mask is applied after dermarolling. When your face has dried, you can apply Infadolan ointment to selected spots.  Our masks contain 2000 ppm GHK-Cu/a>. [url=http://www.owndoc.com/dermarolling/copper-peptides-for-dermarolling/]GHK-Cu is the best copper peptide for skin rejuvenation and collagen regeneration.

Buy our copper peptide facial mask

<strong>Ingredient list:</strong>

          Carbomer (Carboxypolymethylene) 10 %

          TEA (Triethanol amine) 0.1 %

          Hyaluronic Acid 0.3 %

          GHK-Cu 0.1 % (1000 ppm)

          Nano Platinum 0.1 %

          Centella Extract 2 %

          Yam Extract 2 %

          Syn-Coll (PALMITOYL TRIPEPTIDE-3) 2 %

          Vitamin B3 0.2 %

          Vitamin B5 0.3 %

          1,3 Butylene Glycol 5 %

          Propylene Glycol 3 %

          Propyl paraben 0.1 %

          Tween 20 0.1 %

          Fragrance 0.01 %

          The rest is deionized water.

  It is found that in poor connective tissue conditions, the triterpenes in<strong> Centella asiatica</strong> are able to renew the collagen, in quantity and quality, and restore tissue firmness and skin elasticity, improving skin appearance and comfort. Apart from this it also has anti-psoriatic properties.

          (Reference Aesthetic Plastic Surgery, May-June 2000, pages 227-234;

          Phytomedicine, May 2001, pages 230-235; and Contact Dermatitis, October 1993, pages 175-179)

          <strong>Pantothenic acid, also called vitamin B5</strong>

          Wound Healing

          A study in 1999 showed that pantothenic acid has an effect on wound healing

          in vitro[51]. Wiemann and Hermann found that cell cultures with a

          concentration of 100μg/mL calcium D-pantothenate increased migration, and

          the fibres ran directionally with several layers, whereas the cell cultures

          without pantothenic acid healed in no orderly motion, and with fewer

          layers[52]. Cell proliferation, or cell multiplication was found to increase

          with pantothenic acid supplementation[53]. Finally, there were increased

          concentrations of two proteins, both of which have still to be been

          identified, that was found in the supplemented culture, but not on the

          control[54]. Further studies are needed to determine whether these effects

          will stand in vivo.

          <strong>Acne</strong>

          Following from discoveries in mouse trials, in the late 1990s a small study

          was published promoting the use of pantothenic acid to treat acne vulgaris.

          According to a study published in 1995 by Dr. Lit-Hung Leung,[62] high doses

          of Vitamin B5 resolved acne and decreased pore size. Dr. Leung also proposes

          a mechanism, stating that CoA regulates both hormones and fatty-acids, and

          without sufficient quantities of pantothenic acid, CoA will preferentially

          produce androgens. This causes fatty acids to build up and be excreted

          through sebaceous glands, causing acne. Leung's study gave 45 Asian males

          and 55 Asian females varying doses of 10-20g of pantothenic acid (100000% of

          the US Daily Value), 80% orally and 20% through topical cream. Leung noted

          improvement of acne within one week to one month of the start of the

          treatment.

          http://en.wikipedia.org/wiki/Pantothenic_acid

          <strong>Topical Use of Dexpanthenol in Skin Disorders</strong>

          Authors: Ebner F.1; Heller A.2; Rippke F.2; Tausch I.3

          Source: American Journal of Clinical Dermatology, Volume 3, Number 6, 1 June

          2002 , pp. 427-433(7)

          Publisher: Adis International

          Abstract:

          Pantothenic acid is essential to normal epithelial function. It is a

          component of coenzyme A, which serves as a cofactor for a variety of

          enzyme-catalyzed reactions that are important in the metabolism of

          carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid

          hormones, and porphyrins. The topical use of dexpanthenol, the stable

          alcoholic analog of pantothenic acid, is based on good skin penetration and

          high local concentrations of dexpanthenol when administered in an adequate

          vehicle, such as water-in-oil emulsions. Topical dexpanthenol acts like a

          moisturizer, improving stratum corneum hydration, reducing

          transepidermal water loss and maintaining skin softness and elasticity.

          Activation of fibroblast proliferation, which is of relevance in wound healing, has been

          observed both in vitro and in vivo with dexpanthenol. Accelerated

          re-epithelization in wound healing, monitored by means of the transepidermal

          water loss as an indicator of the intact epidermal barrier function, has

          also been seen. Dexpanthenol has been shown to have an anti-inflammatory

          effect on experimental ultraviolet-induced erythema.

          Beneficial effects of dexpanthenol have been observed in patients who have

          undergone skin transplantation or scar treatment, or therapy for burn

          injuries and different dermatoses. The stimulation of epithelization,

          granulation and mitigation of itching were the most prominent effects of

          formulations containing dexpanthenol. In double-blind placebo-controlled

          clinical trials, dexpanthenol was evaluated for its efficacy in improving

          wound healing. Epidermal wounds treated with dexpanthenol emulsion showed a

          reduction in erythema, and more elastic and solid tissue regeneration.

          Monitoring of transepidermal water loss showed a significant acceleration of

          epidermal regeneration as a result of dexpanthenol therapy, as compared with

          the vehicle. In an irritation model, pretreatment with dexpanthenol cream

          resulted in significantly less damage to the stratum corneum barrier,

          compared with no pretreatment. Adjuvant skin care with dexpanthenol

          considerably improved the symptoms of skin irritation, such as dryness of

          the skin, roughness, scaling, pruritus, erythema, erosion/fissures, over 3

          to 4 weeks. Usually, the topical administration of dexpanthenol preparations

          is well tolerated, with minimal risk of skin irritancy or sensitization.

1859
Dermarolling / Microneedling / iodine scar reduction
« on: May 03, 2010, 08:23:47 AM »
You can give it a try. The problem is that after needling, the iodine will penetrate deeply and some of it will likely get into the blood stream. Iodine, just like any other toxic element should not be overdosed so Lugol's solution should not be put on extensive areas or for a very long time, especially if you apply it after needling.

Try it on a small area. Iodine is used to disinfect wounds so it is OK to use it for its intended purpose, but I would not recommend prolonged use on large "open" areas, since Iodine is a toxic halogen.

Then again, many, if not most people have an Iodine deficiency, and Iodine protects against heavy metal accumulation and many other serious problems. Iodine is one of the most important elements for our health. So as long as you don't overdo it, you should be fine.


1860
Dermarolling / Microneedling / iodine scar reduction
« on: April 29, 2010, 02:38:01 PM »
Regeneration of Human Scar Tissue with Topical Iodine

 

  A Preliminary Report

     

  David M. Derry, MD, PhD

 

  part 1

 

  http://www.owndoc.com/pdf/Derry%20Iodine%20Regeneration-1.pdf

 

  part 2

 

  http://www.owndoc.com/pdf/Derry%20Iodine%20Regeneration-2.pdf